Menstrual cycle and menopause. Part 4.

 

In the second phase of menopause, there is a decrease in estrogen concentration and excessive release of pituitary gonadotropins (FSH and LH). The consequences of these changes are vasomotor disorders: facial erythema, feeling of heat, feeling of rushing blood to the head, palpitations, fluctuations in blood pressure.

 

Hyperactivity of the pituitary gland in the secretion of gonadotropins causes hyperactivity of the reticular zone of the adrenal cortex in the secretion and release of 17-ketosteroids (17-ketosteroids are a group of metabolites formed in the metabolism of androgens produced in the adrenal glands and hilar cells of the ovaries, i.e. testosterone, DHEA-S, and less often DHEA and androstenedione ). Symptoms of this include: thickening of the voice, development of excessive hair, and masculinization of some facial features of the woman.